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    INTRODUCTION State-of-the-art clinical positron emission tomography (PET) scanners utilize detector blocks consisting of many pixelated scintillation crystals. First systems in the preclinical domain are now based on monolithic crystal blocks showing a remarkable performance which also makes it potentially interesting for clinical PET [1][2].

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    2016-2-16 · While the first time-of-flight (TOF)-positron emission tomography (PET) systems were already built in the early 1980s, limited clinical studies were acquired on these scanners. PET was still a research tool, and the available TOF-PET systems were experimental. Due to a combination of low stopping power and limited spatial resolution (caused by limited light output of the scintillators), these ...

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    2020-5-25 · The idea of a very sensitive positron emission tomography (PET) system covering a large portion of the body of a patient already dates back to the early 1990s. In the period 2000–2010, only some prototypes with long axial field of view (FOV) have been built, which never resulted in systems used for clinical research. One of the reasons was the limitations in the available detector technology ...

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    After explaining the different detector concepts for integrating PET-MRI and minimising interference the limitations and advantages of different solutions for the detector and system are described for preclinical and clinical imaging systems. The different integrated PET-MRI systems are described in detail.

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